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Defective T cell Receptor-mediated Signal Transduction in Memory CD4 T Lymphocytes Exposed to Superantigen or anti-T cell Receptor Antibodies

Lymphocytes must promote protective immune responses while still maintaining self-tolerance. Stimulation through the T cell receptor (TCR1) can lead to distinct responses in naive and memory CD4 T cells. Whereas peptide antigen stimulates both naive and memory T cells, soluble anti-CD3 antibodies an...

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Detalhes bibliográficos
Main Authors: Watson, Andrew R.O., Lee, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829409/
https://ncbi.nlm.nih.gov/pubmed/17083922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2006.09.008
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