Recruitment of P-TEFb (Cdk9-Pch1) to chromatin by the cap-methyl transferase Pcm1 in fission yeast

Capping of nascent pre-mRNAs is thought to be a prerequisite for productive elongation and associated serine 2 phosphorylation of the C-terminal domain (CTD) of RNA polymerase II (PolII). The mechanism mediating this link is unknown, but is likely to include the capping machinery and P-TEPb. We repo...

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Bibliografiska uppgifter
Huvudupphovsmän: Guiguen, Allan, Soutourina, Julie, Dewez, Monique, Tafforeau, Lionel, Dieu, Marc, Raes, Martine, Vandenhaute, Jean, Werner, Michel, Hermand, Damien
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829387/
https://ncbi.nlm.nih.gov/pubmed/17332744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601627
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