PACAP type I receptor transactivation is essential for IGF-1 receptor signalling and antiapoptotic activity in neurons

Insulin-like growth factor-1 (IGF-1) and pituitary adenylyl cyclase activating polypeptide (PACAP) are both potent neurotrophic and antiapoptotic factors, which exert their effects via phosphorylation cascades initiated by tyrosine kinase and G-protein-coupled receptors, respectively. Here, we have...

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Detalhes bibliográficos
Main Authors: Delcourt, Nicolas, Thouvenot, Eric, Chanrion, Benjamin, Galéotti, Nathalie, Jouin, Patrick, Bockaert, Joël, Marin, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829375/
https://ncbi.nlm.nih.gov/pubmed/17332755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601608
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