Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice

Transition nuclear proteins (TPs), the major proteins found in chromatin of condensing spermatids, are believed to be important for histone displacement and chromatin condensation during mammalian spermatogenesis. We generated mice lacking the major TP, TP1, by targeted deletion of the Tnp1 gene in...

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Autors principals: Yu, Y. Eugene, Zhang, Yun, Unni, Emmanual, Shirley, Cynthia R., Deng, Jian M., Russell, Lonnie D., Weil, Michael M., Behringer, Richard R., Meistrich, Marvin L.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18293/
https://ncbi.nlm.nih.gov/pubmed/10781074
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