Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model

Androgens influence transcription of their target genes through the activation of the androgen receptor (AR) that subsequently interacts with specific DNA motifs in these genes. These DNA motifs, called androgen response elements (AREs), can be classified in two classes: the classical AREs, which ar...

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Hauptverfasser: Schauwaers, Kris, De Gendt, Karel, Saunders, Philippa T. K., Atanassova, Nina, Haelens, Annemie, Callewaert, Leen, Moehren, Udo, Swinnen, Johannes V., Verhoeven, Guido, Verrijdt, Guy, Claessens, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829247/
https://ncbi.nlm.nih.gov/pubmed/17360365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610814104
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