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Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II

Type II DNA topoisomerases are essential and ubiquitous enzymes that perform important functions in chromosome condensation and segregation and in regulating intracellular DNA supercoiling. Topoisomerases carry out these DNA transactions by passing one segment of DNA through the other by using a rev...

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Bibliografiska uppgifter
Huvudupphovsmän: Smiley, R. Derike, Collins, Tammy R. L., Hammes, Gordon G., Hsieh, Tao-Shih
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829226/
https://ncbi.nlm.nih.gov/pubmed/17360343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700342104
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