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Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II

Type II DNA topoisomerases are essential and ubiquitous enzymes that perform important functions in chromosome condensation and segregation and in regulating intracellular DNA supercoiling. Topoisomerases carry out these DNA transactions by passing one segment of DNA through the other by using a rev...

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Detalhes bibliográficos
Main Authors: Smiley, R. Derike, Collins, Tammy R. L., Hammes, Gordon G., Hsieh, Tao-Shih
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829226/
https://ncbi.nlm.nih.gov/pubmed/17360343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700342104
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