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The Sensitivity of the OptiMAL Rapid Diagnostic Test to the Presence of Plasmodium falciparum Gametocytes Compromises Its Ability To Monitor Treatment Outcomes in an Area of Papua New Guinea in which Malaria Is Endemic

Using in vivo samples from treatment failure malaria cases, we demonstrate the high sensitivity of the parasite lactase dehydrogenase (pLDH)-based OptiMAL rapid diagnostic test in the detection of P. falciparum gametocytes. This high sensitivity limits the use of pLDH-based tests in the monitoring o...

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Detalhes bibliográficos
Main Authors: Mueller, Ivo, Betuela, Inoni, Ginny, Meza, Reeder, John C., Genton, Blaise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829017/
https://ncbi.nlm.nih.gov/pubmed/17135432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00816-06
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