Detection of Multidrug Resistance in Mycobacterium tuberculosis

We developed a DNA sequencing-based method to detect mutations in the genome of drug-resistant Mycobacterium tuberculosis. Drug resistance in M. tuberculosis is caused by mutations in restricted regions of the genome. Eight genome regions associated with drug resistance, including rpoB for rifampin...

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Autors principals: Sekiguchi, Jun-ichiro, Miyoshi-Akiyama, Tohru, Augustynowicz-Kopeć, Ewa, Zwolska, Zofia, Kirikae, Fumiko, Toyota, Emiko, Kobayashi, Intetsu, Morita, Koji, Kudo, Koichiro, Kato, Seiya, Kuratsuji, Tadatoshi, Mori, Toru, Kirikae, Teruo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Mycobacteriology and Aerobic Actinomycetes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828975/
https://ncbi.nlm.nih.gov/pubmed/17108078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00750-06
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