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Lysosomes and Fas-mediated liver cell death

A number of studies, mostly performed ex vivo, suggest that lysosomes are involved in apoptosis as a result of a release of their cathepsins into the cytosol. These enzymes could then contribute to the permeabilization of the outer mitochondrial membrane; they could also activate effector caspases....

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Detalhes bibliográficos
Main Authors: Wattiaux, Robert, Wattiaux-De Coninck, Simone, Thirion, Jacqueline, Gasingirwa, Mańe-Christine, Jadot, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828900/
https://ncbi.nlm.nih.gov/pubmed/17129211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061738
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