Intranasal Coadministration of Live Lactococci Producing Interleukin-12 and a Major Cow's Milk Allergen Inhibits Allergic Reaction in Mice

The Th1/Th2 balance deregulation toward a Th2 immune response plays a central role in allergy. We previously demonstrated that administration of recombinant Lactococcus lactis strains expressing bovine β-lactoglobulin (BLG), a major cow's milk allergen, partially prevents mice from sensitizatio...

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Autores principales: Cortes-Perez, Naima G., Ah-Leung, Sandrine, Bermúdez-Humarán, Luis G., Corthier, Gérard, Wal, Jean-Michel, Langella, Philippe, Adel-Patient, Karine
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Cellular Immunology, Antibodies, and Mediators of Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828845/
https://ncbi.nlm.nih.gov/pubmed/17202306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00299-06
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