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(A)Symmetric Stem Cell Replication and Cancer

Most tissues in metazoans undergo continuous turnover due to cell death or epithelial shedding. Since cellular replication is associated with an inherent risk of mutagenesis, tissues are maintained by a small group of stem cells (SCs) that replicate slowly to maintain their own population and that g...

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Detalhes bibliográficos
Main Authors: Dingli, David, Traulsen, Arne, Michor, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828703/
https://ncbi.nlm.nih.gov/pubmed/17367205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030053
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