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Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiae

Yeast cells lacking the SGS1 DNA helicase and the MUS81 structure-specific endonuclease display a synthetic lethality that is suppressed by loss of the RAD51 recombinase. This epistatic interaction suggests that the primary function of SGS1 or MUS81, or both genes, is downstream of RAD51. To identif...

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Bibliografiset tiedot
Päätekijät: li, Miki, Brill, Steven J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828632/
https://ncbi.nlm.nih.gov/pubmed/16193328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-005-0014-5
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