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Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiae
Yeast cells lacking the SGS1 DNA helicase and the MUS81 structure-specific endonuclease display a synthetic lethality that is suppressed by loss of the RAD51 recombinase. This epistatic interaction suggests that the primary function of SGS1 or MUS81, or both genes, is downstream of RAD51. To identif...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828632/ https://ncbi.nlm.nih.gov/pubmed/16193328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-005-0014-5 |
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