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AcpA Is a Francisella Acid Phosphatase That Affects Intramacrophage Survival and Virulence

AcpA of Francisella spp. is a respiratory-burst-inhibiting acid phosphatase that also exhibits phospholipase C activity. To better understand the molecular basis of AcpA in virulence, a deletion of acpA was constructed in Francisella novicida. The phosphatase and lipase activities were reduced 10-fo...

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Bibliografiske detaljer
Main Authors: Mohapatra, Nrusingh P., Balagopal, Ashwin, Soni, Shilpa, Schlesinger, Larry S., Gunn, John S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828385/
https://ncbi.nlm.nih.gov/pubmed/17060465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01226-06
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