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The role of Axin2 in calvarial morphogenesis and craniosynostosis
Axin1 and its homolog Axin2/conductin/Axil are negative regulators of the canonical Wnt pathway that suppress signal transduction by promoting degradation of β -catenin. Mice with deletion of Axin1 exhibit defects in axis determination and brain patterning during early embryonic development. We show...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828115/ https://ncbi.nlm.nih.gov/pubmed/15790973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.01786 |
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