Polymorphisms of phase II xenobiotic-metabolizing and DNA repair genes and in vitro N-ethyl-N-nitrosourea–induced O(6)-ethylguanine levels in human lymphocytes

This study tested the hypothesis that genetic variants of phase II detoxification enzymes and DNA repair proteins affect individual response to DNA damage from alkylating agents. In 171 healthy individuals, an immunoslot blot assay was used to measure O(6)-ethylguanosine (O(6)-EtGua) adduct levels i...

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Main Authors: Jiao, Li, Chang, Ping, Firozi, Pervez F., Lai, Dejian, Abbruzzese, James L, Li, Donghui
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828113/
https://ncbi.nlm.nih.gov/pubmed/17158087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2006.11.001
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