Antiviral Effects of Geranylgeranylacetone: Enhancement of MxA Expression and Phosphorylation of PKR during Influenza Virus Infection

A cyclic polyisoprenoid compound, geranylgeranylacetone (GGA), has been used as antiulcer drug. GGA is also a potent inducer of heat shock proteins (HSPs). HSPs are considered to induce an antiviral effect; however, the detailed mechanism is unknown. To determine whether GGA might show antiviral act...

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Publicat a:	Antimicrob Agents Chemother
Autors principals:	Unoshima, Masako, Iwasaka, Hideo, Eto, Junko, Takita-Sonoda, Yoshiko, Noguchi, Takayuki, Nishizono, Akira
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2003
Matèries:	Antiviral Agents
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182641/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2914-2921.2003
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