Effects of p21(Waf1/Cip1/Sdi1) on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases

Induction of cyclin-dependent kinase inhibitor p21(Waf1/Cip1/Sdi1) triggers cell growth arrest associated with senescence and damage response. Overexpression of p21 from an inducible promoter in a human cell line induces growth arrest and phenotypic features of senescence. cDNA array hybridization s...

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Detaylı Bibliyografya
Asıl Yazarlar: Chang, Bey-Dih, Watanabe, Keiko, Broude, Eugenia V., Fang, Jing, Poole, Jason C., Kalinichenko, Tatiana V., Roninson, Igor B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2000
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC18232/
https://ncbi.nlm.nih.gov/pubmed/10760295
Etiketler: Etiketle
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