Effects of p21(Waf1/Cip1/Sdi1) on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases
Induction of cyclin-dependent kinase inhibitor p21(Waf1/Cip1/Sdi1) triggers cell growth arrest associated with senescence and damage response. Overexpression of p21 from an inducible promoter in a human cell line induces growth arrest and phenotypic features of senescence. cDNA array hybridization s...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2000
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18232/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10760295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.8.4291 |
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