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A Transition State Analogue for an RNA-Editing Reaction
Deamination at C6 of adenosine in RNA catalyzed by the ADAR enzymes generates inosine at the corresponding position. Because inosine is decoded as guanosine during translation, this modification can lead to codon changes in messenger RNA. Hydration of 8-azanebularine across the C6–N1 double bond gen...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1823040/ https://ncbi.nlm.nih.gov/pubmed/15355102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0472073 |
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