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Long-Term Production of Ergot Peptides by Immobilized Claviceps purpurea in Semicontinuous and Continuous Culture

The semicontinuous and continuous production of pharmaceutically useful ergot peptides with immobilized Claviceps purpurea could be demonstrated. A key aspect was the presence of high concentrations of CaCl(2) (96.9 mM) to give marked prolongation of the productive phase, and cultivation in a bubble...

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Publicat a:Appl Environ Microbiol
Autors principals: Dierkes, Wilfried, Lohmeyer, Michael, Rehm, Hans-Jürgen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182231/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16348979/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.59.7.2029-2033.1993
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