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Long-Term Production of Ergot Peptides by Immobilized Claviceps purpurea in Semicontinuous and Continuous Culture

The semicontinuous and continuous production of pharmaceutically useful ergot peptides with immobilized Claviceps purpurea could be demonstrated. A key aspect was the presence of high concentrations of CaCl(2) (96.9 mM) to give marked prolongation of the productive phase, and cultivation in a bubble...

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Bibliographic Details
Main Authors: Dierkes, Wilfried, Lohmeyer, Michael, Rehm, Hans-Jürgen
Format: Artigo
Language:Inglês
Published: 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC182231/
https://ncbi.nlm.nih.gov/pubmed/16348979
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