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Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension

Hypertension is a clinical syndrome characterized by increased vascular tone. However, the molecular mechanisms underlying vascular dysfunction during acquired hypertension remain unresolved. Localized intracellular Ca(2+) release events through ryanodine receptors (Ca(2+) sparks) in the sarcoplasmi...

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Detalhes bibliográficos
Main Authors: Amberg, Gregory C., Bonev, Adrian D., Rossow, Charles F., Nelson, Mark T., Santana, Luis F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC182211/
https://ncbi.nlm.nih.gov/pubmed/12952920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318684
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