Group B streptococcal β-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis

Meningitis occurs when blood-borne pathogens cross the blood-brain barrier (BBB) in a complex interplay between endothelial cells and microbial gene products. We sought to understand the initial response of the BBB to the human meningeal pathogen group B Streptococcus (GBS) and the organism’s major...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Doran, Kelly S., Liu, George Y., Nizet, Victor
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2003
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12952922/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17335
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