Prenatal dexamethasone exposure induces changes in nonhuman primate offspring cardiometabolic and hypothalamic-pituitary-adrenal axis function

Prenatal stress or glucocorticoid administration has persisting “programming” effects on offspring in rodents and other model species. Multiple doses of glucocorticoids are in widespread use in obstetric practice. To examine the clinical relevance of glucocorticoid programming, we gave 50, 120, or 2...

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Autors principals: de Vries, Annick, Holmes, Megan C., Heijnis, Areke, Seier, Jürgen V., Heerden, Joritha, Louw, Johan, Wolfe-Coote, Sonia, Meaney, Michael J., Levitt, Naomi S., Seckl, Jonathan R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1821070/
https://ncbi.nlm.nih.gov/pubmed/17380204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30982
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