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Prenatal dexamethasone ‘programmes’ hypotension, but stress-induced hypertension in adult offspring

Low birth weight in humans is predictive of hypertension in adult life. Although the mechanisms underlying this link remain unknown, fetal overexposure to glucocorticoids has been implicated. We previously showed that prenatal dexamethasone (DEX) exposure in the rat lowers birth weight and programme...

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Autors principals: O'Regan, David, Kenyon, Christopher J, Seckl, Jonathan R, Holmes, Megan C
Format: Artigo
Idioma:Inglês
Publicat: BioScientifica 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229630/
https://ncbi.nlm.nih.gov/pubmed/18252958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-07-0327
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