The Facioscapulohumeral muscular dystrophy region on 4qter and the homologous locus on 10qter evolved independently under different evolutionary pressure

BACKGROUND: The homologous 4q and 10q subtelomeric regions include two distinctive polymorphic arrays of 3.3 kb repeats, named D4Z4. An additional BlnI restriction site on the 10q-type sequence allows to distinguish the chromosomal origin of the repeats. Reduction in the number of D4Z4 repeats below...

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Dettagli Bibliografici
Autori principali: Rossi, Monica, Ricci, Enzo, Colantoni, Luca, Galluzzi, Giuliana, Frusciante, Roberto, Tonali, Pietro A, Felicetti, Luciano
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1821008/
https://ncbi.nlm.nih.gov/pubmed/17335567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-8
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