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Replication fork stalling and cell cycle arrest in UV-irradiated Escherichia coli

Faithful duplication of the genome relies on the ability to cope with an imperfect template. We investigated replication of UV-damaged DNA in Escherichia coli and found that ongoing replication stops for at least 15–20 min before resuming. Undamaged origins of replication (oriC) continue to fire at...

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Hlavní autoři: Rudolph, Christian J., Upton, Amy L., Lloyd, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820941/
https://ncbi.nlm.nih.gov/pubmed/17369400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.417607
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