In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stability

It has long been thought that signal joints, the byproducts of V(D)J recombination, are not involved in the dynamics of the rearrangement process. Evidence has now started to accumulate that this is not the case, and that signal joints play unsuspected roles in events that might compromise genomic i...

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Détails bibliographiques
Auteurs principaux: Vanura, Katrina, Montpellier, Bertrand, Le, Trang, Spicuglia, Salvatore, Navarro, Jean-Marc, Cabaud, Olivier, Roulland, Sandrine, Vachez, Elodie, Prinz, Immo, Ferrier, Pierre, Marculescu, Rodrig, Jäger, Ulrich, Nadel, Bertrand
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820826/
https://ncbi.nlm.nih.gov/pubmed/17298184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050043
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