In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stability

It has long been thought that signal joints, the byproducts of V(D)J recombination, are not involved in the dynamics of the rearrangement process. Evidence has now started to accumulate that this is not the case, and that signal joints play unsuspected roles in events that might compromise genomic i...

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Detalhes bibliográficos
Main Authors: Vanura, Katrina, Montpellier, Bertrand, Le, Trang, Spicuglia, Salvatore, Navarro, Jean-Marc, Cabaud, Olivier, Roulland, Sandrine, Vachez, Elodie, Prinz, Immo, Ferrier, Pierre, Marculescu, Rodrig, Jäger, Ulrich, Nadel, Bertrand
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820826/
https://ncbi.nlm.nih.gov/pubmed/17298184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050043
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