The Walker B motif of the second nucleotide-binding domain (NBD2) of CFTR plays a key role in ATPase activity by the NBD1–NBD2 heterodimer

CFTR (cystic fibrosis transmembrane conductance regulator), a member of the ABC (ATP-binding cassette) superfamily of membrane proteins, possesses two NBDs (nucleotide-binding domains) in addition to two MSDs (membrane spanning domains) and the regulatory ‘R’ domain. The two NBDs of CFTR have been m...

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Hlavní autoři: Stratford, Fiona L. L., Ramjeesingh, Mohabir, Cheung, Joanne C., Huan, Ling-JUN, Bear, Christine E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820796/
https://ncbi.nlm.nih.gov/pubmed/16989640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060968
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