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Subunit Interaction Determines I(Ks) Participation in Cardiac Repolarization and Repolarization Reserve

BACKGROUND: The role of I(Ks), the slow delayed rectifier K(+) current, in cardiac ventricular repolarization has been a subject of debate. METHODS AND RESULTS: We develop a detailed Markov model of I(Ks) and its α-subunit KCNQ1 and examine their kinetic properties during the cardiac ventricular act...

詳細記述

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書誌詳細
主要な著者: Silva, Jonathan, Rudy, Yoram
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820744/
https://ncbi.nlm.nih.gov/pubmed/16129795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.105.543306
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