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Subunit Interaction Determines I(Ks) Participation in Cardiac Repolarization and Repolarization Reserve
BACKGROUND: The role of I(Ks), the slow delayed rectifier K(+) current, in cardiac ventricular repolarization has been a subject of debate. METHODS AND RESULTS: We develop a detailed Markov model of I(Ks) and its α-subunit KCNQ1 and examine their kinetic properties during the cardiac ventricular act...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820744/ https://ncbi.nlm.nih.gov/pubmed/16129795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.105.543306 |
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