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Design of cyclic and other templates for potent and selective peptide α-MSH analogues
For over three decades, the design of linear peptide ligands often has incorporated cyclic constraints to improve potency, receptor selectivity, proteolytic stability and biodistribution. Its importance has been so well established that modern day schemes for ligand-based drug design often start wit...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820743/ https://ncbi.nlm.nih.gov/pubmed/16023401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2005.06.010 |
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