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Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1

Silencing gene expression by RNAi is a powerful method for exploring gene function and validating drug targets and potentially for therapy. Lymphocytes and other primary blood cells are resistant to lipid-based transfection in vitro and are difficult to target in vivo. We show here that antibody-pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Peer, Dan, Zhu, Pengcheng, Carman, Christopher V., Lieberman, Judy, Shimaoka, Motomu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820714/
https://ncbi.nlm.nih.gov/pubmed/17360483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608491104
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