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KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging

Population profiles of industrialized countries show dramatic increases in cardiovascular disease with age, but the molecular and genetic basis of disease progression has been difficult to study because of the lack of suitable model systems. Our studies of Drosophila show a markedly elevated inciden...

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Detalhes bibliográficos
Main Authors: Ocorr, Karen, Reeves, Nick L., Wessells, Robert J., Fink, Martin, Chen, H.-S. Vincent, Akasaka, Takeshi, Yasuda, Soichiro, Metzger, Joseph M., Giles, Wayne, Posakony, James W., Bodmer, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820688/
https://ncbi.nlm.nih.gov/pubmed/17360457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609278104
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