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Pharmacological inhibition of poly(ADP-ribose) polymerase inhibits angiogenesis

Poly(ADP-ribose)polymerase (PARP) is a nuclear enzyme which plays an important role in regulating cell death and cellular responses to DNA repair. Pharmacological inhibitors of PARP are being considered as treatment for cancer both in monotherapy as well as in combination with chemotherapeutic agent...

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Hlavní autoři: Rajesh, Mohanraj, Mukhopadhyay, Partha, Bátkai, Sándor, Godlewski, Grzegorz, Haskó, György, Liaudet, Lucas, Pacher, Pál
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820627/
https://ncbi.nlm.nih.gov/pubmed/17007818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.09.049
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