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X-Linked G6PD Deficiency Protects Hemizygous Males but Not Heterozygous Females against Severe Malaria
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) is important in the control of oxidant stress in erythrocytes, the host cells for Plasmodium falciparum. Mutations in this enzyme produce X-linked deficiency states associated with protection against malaria, notably in Africa where the A− form of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820604/ https://ncbi.nlm.nih.gov/pubmed/17355169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040066 |
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