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DNA-Dependent Protein Kinase Catalytic Subunit Is Not Required for Dysfunctional Telomere Fusion and Checkpoint Response in the Telomerase-Deficient Mouse

Telomeres are key structural elements for the protection and maintenance of linear chromosomes, and they function to prevent recognition of chromosomal ends as DNA double-stranded breaks. Loss of telomere capping function brought about by telomerase deficiency and gradual erosion of telomere ends or...

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Main Authors: Maser, Richard S., Wong, Kwok-Kin, Sahin, Erguen, Xia, Huili, Naylor, Maria, Hedberg, H. Mason, Artandi, Steven E., DePinho, Ronald A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2007
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820500/
https://ncbi.nlm.nih.gov/pubmed/17145779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01354-06
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