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The Bloom's Syndrome Helicase Is Critical for Development and Function of the αβ T-Cell Lineage

Bloom's syndrome is a genetic disorder characterized by increased incidence of cancer and an immunodeficiency of unknown origin. The BLM gene mutated in Bloom's syndrome encodes a DNA helicase involved in the maintenance of genomic integrity. To explore the role of BLM in the immune system...

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Detalhes bibliográficos
Main Authors: Babbe, Holger, Chester, Nicholas, Leder, Philip, Reizis, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820471/
https://ncbi.nlm.nih.gov/pubmed/17210642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01402-06
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