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DNA oxidation matters: The HPLC–electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine

Oxidative DNA damage is important in aging and the degenerative diseases of aging such as cancer. Estimates commonly rely on measurements of 8-oxo-2′-deoxyguanosine (oxo(8)dG), an adduct that occurs in DNA and is also excreted in urine after DNA repair. Here we examine difficulties inherent in the a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Helbock, Harold J., Beckman, Kenneth B., Shigenaga, Mark K., Walter, Patrick B., Woodall, Alan A., Yeo, Helen C., Ames, Bruce N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC18204/
https://ncbi.nlm.nih.gov/pubmed/9419368
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