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Dose-dependent pharmacokinetics of mezlocillin in relation to renal impairment.

The dose dependence of mezlocillin pharmacokinetics was examined in relation to renal function after intravenous doses of 1 and 5 g in 16 subjects with various degrees of renal impairment. Dose and time-average model-independent physiological parameters were calculated from plasma concentration and...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Mangione, A, Boudinot, F D, Schultz, R M, Jusko, W J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1982
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181910/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6213190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.3.428
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