Dose-dependent pharmacokinetics of mezlocillin in relation to renal impairment.

The dose dependence of mezlocillin pharmacokinetics was examined in relation to renal function after intravenous doses of 1 and 5 g in 16 subjects with various degrees of renal impairment. Dose and time-average model-independent physiological parameters were calculated from plasma concentration and...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Mangione, A, Boudinot, F D, Schultz, R M, Jusko, W J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6213190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.3.428
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