Pharmacokinetics and bacteriological efficacy of N-formimidoyl thienamycin in experimental Escherichia coli meningitis.

The pharmacokinetics and bacteriological efficacy of N-formimidoyl thienamycin were determined in rabbits infected with Escherichia coli K1. After a single intravenous dose of 25 mg/kg, a peak N-formimidoyl thienamycin concentration in cerebrospinal fluid (CSF) of 2.5 micrograms/ml was attained at 4...

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Bibliografske podrobnosti
Main Authors: Patamasucon, P, McCracken, G H
Format: Artigo
Jezik:Inglês
Izdano: 1982
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC181901/
https://ncbi.nlm.nih.gov/pubmed/7049073
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