Requirement of dendritic calcium spikes for induction of spike-timing-dependent synaptic plasticity

Spike-timing-dependent synaptic plasticity (STDP) by definition requires the temporal association of pre- and postsynaptic action potentials (APs). Yet, in cortical pyramidal neurons pairing unitary EPSPs with single APs at low frequencies is ineffective at generating plasticity. Using recordings fr...

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Bibliographic Details
Main Authors: Kampa, Björn M, Letzkus, Johannes J, Stuart, Greg J
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2006
Subjects:
Skeletal Muscle and Exercise
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817800/
https://ncbi.nlm.nih.gov/pubmed/16675489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.111062
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