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Kinetics of Mg(2+) unblock of NMDA receptors: implications for spike-timing dependent synaptic plasticity

The time course of Mg(2+) block and unblock of NMDA receptors (NMDARs) determines the extent they are activated by depolarization. Here, we directly measure the rate of NMDAR channel opening in response to depolarizations at different times after brief (1 ms) and sustained (4.6 s) applications of gl...

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Autors principals: Kampa, Björn M, Clements, John, Jonas, Peter, Stuart, Greg J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664940/
https://ncbi.nlm.nih.gov/pubmed/14754998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.058842
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