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Kinetics of Mg(2+) unblock of NMDA receptors: implications for spike-timing dependent synaptic plasticity

The time course of Mg(2+) block and unblock of NMDA receptors (NMDARs) determines the extent they are activated by depolarization. Here, we directly measure the rate of NMDAR channel opening in response to depolarizations at different times after brief (1 ms) and sustained (4.6 s) applications of gl...

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Bibliografski detalji
Glavni autori: Kampa, Björn M, Clements, John, Jonas, Peter, Stuart, Greg J
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664940/
https://ncbi.nlm.nih.gov/pubmed/14754998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.058842
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