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l-Arginine supplementation or arginase inhibition augments reflex cutaneous vasodilatation in aged human skin

Full expression of reflex cutaneous vasodilatation is dependent on nitric oxide (NO) and vasodilatation is attenuated in healthy older humans. NO bioavailability in aged skin may be decreased by an age-related upregulation of arginase, which reciprocally regulates the NO-synthase (NOS) substrate l-a...

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Main Authors: Holowatz, Lacy A, Thompson, Caitlin S, Kenney, W Larry
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817757/
https://ncbi.nlm.nih.gov/pubmed/16675494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.108993
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