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The Arg16Gly polymorphism of the β(2)-adrenergic receptor and the natriuretic response to rapid saline infusion in humans

The β(2)-adrenergic receptors (β(2)ARs) play a role in renal Na(+) regulation. Subjects homozygous for glycine at amino acid 16 (Gly16) of the β(2)AR have been shown to have enhanced β(2)-mediated vascular relaxation when compared to subjects homozygous for arginine (Arg16). However, Gly16 subjects...

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Autori principali: Snyder, Eric M, Turner, Stephen T, Joyner, Michael J, Eisenach, John H, Johnson, Bruce D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817726/
https://ncbi.nlm.nih.gov/pubmed/16728452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.107672
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