Mechanisms of Acquired Androgen Independence during Arsenic-Induced Malignant Transformation of Human Prostate Epithelial Cells

BACKGROUND: Prostate cancer progression often occurs with overexpression of growth factors and receptors, many of which engage the Ras/mitogen-activated protein MAP kinase (MAPK) pathway. OBJECTIVES: In this study we used arsenic-transformed human prostate epithelial cells, which also show androgen-...

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Bibliographic Details
Main Authors: Benbrahim-Tallaa, Lamia, Webber, Mukta M., Waalkes, Michael P.
Format: Artigo
Language:Inglês
Published: National Institute of Environmental Health Sciences 2007
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817693/
https://ncbi.nlm.nih.gov/pubmed/17384772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9630
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