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The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development

The epithelial isoform of fibroblast growth factor receptor 2 (Fgfr2b) is essential for embryogenesis, and Fgfr2b-null mice die at birth. Using Cre-Lox transgenics to delete Fgfr2b in cells expressing keratin 5, we show that mice lacking epidermal Fgfr2b survive into adulthood but display striking a...

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Bibliografische gegevens
Hoofdauteurs: Grose, Richard, Fantl, Vera, Werner, Sabine, Chioni, Athina-Myrto, Jarosz, Monika, Rudling, Robert, Cross, Barbara, Hart, Ian R, Dickson, Clive
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817631/
https://ncbi.nlm.nih.gov/pubmed/17304214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601583
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