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The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development
The epithelial isoform of fibroblast growth factor receptor 2 (Fgfr2b) is essential for embryogenesis, and Fgfr2b-null mice die at birth. Using Cre-Lox transgenics to delete Fgfr2b in cells expressing keratin 5, we show that mice lacking epidermal Fgfr2b survive into adulthood but display striking a...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1817631/ https://ncbi.nlm.nih.gov/pubmed/17304214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601583 |
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